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Create Adverse Event Table

Source: R/safety_tables.R
create_ae_table.Rd

Unified function for generating standard adverse event tables for HTA dossiers and clinical study reports. Supports multiple table types through a single interface.

Usage

create_ae_table(
  adae,
  adsl = NULL,
  type = c("overview", "soc", "soc_pt", "pt", "common", "severity", "relationship",
    "sae", "discontinuation", "deaths"),
  trt_var = "TRT01A",
  n_top = 15,
  soc = NULL,
  title = NULL,
  autofit = TRUE
)

Arguments

adae

ADAE data frame (ADaM Adverse Events dataset)

adsl

ADSL data frame (optional, required for some table types like "deaths" or for denominator calculation)

type

Character string specifying the table type:

  • "overview" - Summary of TEAEs, related AEs, SAEs, discontinuations

  • "soc" - AEs by System Organ Class

  • "soc_pt" - AEs by SOC and Preferred Term (hierarchical)

  • "pt" - AEs by Preferred Term only

  • "common" - Most frequently reported AEs

  • "severity" - AEs by maximum severity

  • "relationship" - AEs by relationship to study drug

  • "sae" - Serious Adverse Events

  • "discontinuation" - AEs leading to discontinuation

  • "deaths" - Deaths summary (requires adsl)

trt_var

Treatment variable name (default: "TRT01A")

n_top

For type="common", number of top PTs to show (default: 15)

soc

For type="pt", filter to specific SOC (optional)

title

Table title (auto-generated if NULL)

autofit

Logical, whether to autofit column widths (default: TRUE)

Value

A ClinicalTable object

Examples

if (FALSE) { # \dontrun{
# AE Overview
overview <- create_ae_table(adae, adsl, type = "overview")

# SOC table
soc_table <- create_ae_table(adae, adsl, type = "soc")

# SOC/PT hierarchical table
soc_pt <- create_ae_table(adae, adsl, type = "soc_pt")

# Most common AEs (top 20)
common <- create_ae_table(adae, adsl, type = "common", n_top = 20)

# SAE table
sae <- create_ae_table(adae, adsl, type = "sae")
} # }