Calculate AE Comparisons for All Treatment Groups vs Reference

Internal helper function that computes risk differences, risk ratios, and associated statistics for all treatment groups compared to a reference.

Usage

.calculate_ae_comparisons(
  ae_wide,
  trt_n,
  trt_groups,
  ref_group,
  trt_var,
  conf_level,
  include_nnh
)

Arguments

ae_wide

Wide-format AE counts with columns for each treatment's n and N values

trt_n

Treatment counts data frame

trt_groups

Treatment groups to compare (excluding reference)

ref_group

Reference group name

trt_var

Treatment variable name

conf_level

Confidence level for intervals

include_nnh

Logical, include NNH calculations

Value

Modified ae_wide data frame with additional columns for statistics