Calculate Risk Difference and Confidence Interval for AE

Calculates risk difference, risk ratio, and associated confidence intervals and p-values for comparing adverse event incidence between two groups. Uses Wald method for RD CI and log-transformation for RR CI.

Usage

calculate_ae_risk_difference(n1, N1, n2, N2, conf_level = 0.95)

Arguments

n1

Number of subjects with event in treatment group

N1

Total subjects in treatment group

n2

Number of subjects with event in reference group

N2

Total subjects in reference group

conf_level

Confidence level (default: 0.95)

Value

List with rd (risk difference), rd_lower, rd_upper, rr (risk ratio), rr_lower, rr_upper, p_value